Sub-threshold spinal cord stimulation facilitates spontaneous motor activity in spinal rats
نویسندگان
چکیده
منابع مشابه
Spinal stimulation of the upper lumbar spinal cord modulates urethral sphincter activity in rats after spinal cord injury.
After spinal cord injury (SCI), the neurogenic bladder is observed to develop asynchronous bladder and external urethral sphincter (EUS) contractions in a condition known as detrusor-sphincter dyssnergia (DSD). Activation of the EUS spinal controlling center located at the upper lumbar spinal cord may contribute to reduce EUS dyssynergic contractions and decrease urethral resistance during void...
متن کاملTargeted, activity-dependent spinal stimulation produces long-lasting motor recovery in chronic cervical spinal cord injury.
Use-dependent movement therapies can lead to partial recovery of motor function after neurological injury. We attempted to improve recovery by developing a neuroprosthetic intervention that enhances movement therapy by directing spike timing-dependent plasticity in spared motor pathways. Using a recurrent neural-computer interface in rats with a cervical contusion of the spinal cord, we synchro...
متن کاملSpinal stimulation of the upper lumbar spinal cord modulates urethral sphincter activity 1 in rats after spinal cord injury 2 Running head: Spinal stimulation modulates urethral sphincter activation
21 After spinal cord injury (SCI), the neurogenic bladder is observed to develop asynchronous 22 bladder and external urethral sphincter (EUS) contractions in a condition known as detrusor 23 sphincter dyssnergia (DSD). Activation of the EUS spinal controlling center located at upper 24 lumbar spinal cord may contribute to reduce EUS dyssynergic contractions and decrease urethral 25 resistance ...
متن کاملEffect of coenzyme Q10 on neuropathic pain threshold resulting from spinal cord injury in male rats
Introduction: Coenzyme Q10 is a powerful antioxidant that has the ability to reduce the damage caused by oxidative stress and is predominantly found in the inner mitochondrial membrane. This study was conducted to determine the effect of coenzyme Q10 on neuropathic pain in an animal model of spinal cord injury. Methods: In order to induce neuropathic pain, thoracic segments of the spinal cor...
متن کاملAugmentation of Voluntary Locomotor Activity by Transcutaneous Spinal Cord Stimulation in Motor-Incomplete Spinal Cord-Injured Individuals.
The level of sustainable excitability within lumbar spinal cord circuitries is one of the factors determining the functional outcome of locomotor therapy after motor-incomplete spinal cord injury. Here, we present initial data using noninvasive transcutaneous lumbar spinal cord stimulation (tSCS) to modulate this central state of excitability during voluntary treadmill stepping in three motor-i...
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ژورنال
عنوان ژورنال: Journal of NeuroEngineering and Rehabilitation
سال: 2013
ISSN: 1743-0003
DOI: 10.1186/1743-0003-10-108